BioNMR in Drug Research

BioNMR in Drug Research
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Transporters as Drug Targets Raimund Mannhold.

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Reactive Drug Metabolites Amit S. Protein-Ligand Interactions Raimund Mannhold. Proteomics in Drug Research Raimund Mannhold.

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Phosphodiesterases and Their Inhibitors Raimund Mannhold. Back cover copy The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich.

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Editied by a former coworker of Wuthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. This interaction can now be investigated in a hitherto unparalleled precision and displayed in 3D-an important prerequisite for the targeted development of new active substances, The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical reseach.

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With its successful mixture of basic information and application strategies, coupled with many real-life examples, this is an invaluable guide for both NMR spectroscopists and pharmaceutical researchers. Table of contents Preface. List of Authors.

List of Abbreviations. Patzelt, et al. Bader, et al.

Orientational Restraints E. Dingley, et al. Williamson , et al. Marchioro, et al.

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Share. Email; Facebook; Twitter; Linked In; Reddit; CiteULike. View Table of Contents for BioNMR in Drug Research. The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical research. Thus it.

Isotope Filter and Editing Techniques G. Blommers, et al. Pellecchia, et al. Subject Index. Review Text "The editor has managed to recruit a team of well-recognized experts as authors for this book, thereby ensuring a high standard of reliable and objective reporting.

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The book is not only of interest to specialists in pharmaceutical research and development, but will certainly also be a valuable resource for everyone concerned with the latest methods of NMR spectroscopy and their application to biomolecules" Angewandte Chemie Int. Edition show more.

Molecular biology methods in drug discovery & development

Review quote " He received his Ph. From to he we was a postdoc with Kurt Wuthrich at the Federal Technical University of Switzerland ETH working on the design of pulse sequences for isotopic ally labeled proteins.

Oliver Zerbe is presently head of the NMR facilities and lecturer of the Institute of Organic Chemistry of the University of Zurich where he became a Privatdozent in and Titular professor in Learn about new offers and get more deals by joining our newsletter. Sign up now. Thus it comes as no surprise that a large number of the authors are working for leading pharmaceutical companies.

With its successful mixture of basic information and application strategies, coupled with many real-life examples, this is an invaluable guide for both NMR spectroscopists and pharmaceutical researchers.

Inni boken. NMR of Biomolecules. Bibliografisk informasjon. Structure Calculation Using Automated Techniques. BioNMR in drug research Methods and principles in medicinal chemistry.